How’s This for The Science Fair.
A PCR machine in the science world is like a photocopier for the business world — it’s a staple in not only various laboratory research (such as genetic screens to identify Congenital Heart Disease-causing mutations), but in crime-scene forensics and heredity tests.
A Polymerase chain reaction is a way to amplify a piece of DNA to generate thousands to millions of copies of a sequence. Using primers, nucleotides, and the enzyme Taq polymerase as the DNA copying reagents, the PCR machines change temperatures for certain periods of time to undergo temperature-sensitive reactions and maximize the annealing processes for the PCR primers.
Professional machines usually are $10,000 dollars each. However, Russell Durrett built one himself for a fraction of the cost — using PVC pipes, a 150-watt lightbulb, a computer fan, a cheap microcontroller, and a few reagents he ordered online.
Check it out how to make it here: